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Your partner for COVID-19 oligonucleotide synthesis. Delivering results, accelerating research and shaping future discoveries. All current genetic testing ...
When customers ask us for tricky oligos, we can often suggest new ways of making them based on research that has not even been published, all without ...
Genes that are not needed in a particular cell are switched off (silenced) ... Cytosine methylation indicates gene silencing: methylated genes are not transcribed.
If mutations survive without being corrected, they can be passed down to ... of Watson-Crick base pairing is not sufficient to maintain genetic integrity, and it is ...
The solid support is then imaged and nucleotides that have not been ... As the cost of DNA sequencing goes down, it will become more widespread, which ...
This is not an ideal situation from a pharmaceutical standpoint, but it has not ... for the endosomes to break down and release their contents into the cytoplasm.
By convention, the prefixes 5′- and 3′- are not written, and nucleic acid ... front of the molecule facing the observer slopes down from top right to bottom left.
PNA is not a nucleic acid, but a neutral molecule. ... were found to be resistant to degradation in serum, have reduced toxicity and reduced off-target effects.
However, synthesis yields fall off dramatically when oligonucleotides more ... It is not unreasonable to expect a yield of 99.5% during each coupling step, but ...
Visit Website Request Information/Quote Download PDF Copy. ATDBio was established to provide high quality oligonucleotides to scientists around the world.