18 Jan 2011 ... We find that KIR3DL1 down-regulation enhances in vitro function, ... Normal T cells express very few or no KIRs, but KIR expression can be detected on a small ... Author contributions: H.Q., Z.W., A.D.R., and C.-P.L. designed ...
4 Sep 2017 ... Here we demonstrate that Kupffer cells (KCs) - the liver-resident macrophages - are EPO targets. ... up to date browser (or turn off compatibility mode in Internet Explorer). ... While total liver cells from LysM cre -Epor fl/fl mice did not exhibit a ... Abram, C. L., Roberge, G. L., Hu, Y. & Lowell, C. A. Comparative ...
DOWN-REGULATION OF ETb RECEPTOR, BUT NOT ETa RECEPTOR, IN CONGESTIVE LUNG SECONDARY TO HEART FAILURE. ARE MARKED ...
23 Mar 2015 ... Roles of cGMP, PKG and Rho-GTPase signalling in the effects of NO ... Based on pull-down assays, it was found that the expression of the ... Di Lorenzo A, Lin MI, Murata T, Landskroner-Eiger S, Schleicher M, Kothiya M, et al.
Androgen receptor down regulation has been generally disproven, rather ... Doc, I'm not advocating a down regulation theory. ... http://thinksteroids.com/forum/steroid-forum/your-androgen-receptors-saturated-134313630.html
Degradation or “down-regulation” of protease-activated receptor-1 (PAR1), a G ... Published Online:3 Apr 2002https://doi.org/10.1091/mbc.e01-11-0131. About ... The overexpression of SNX1 also did not effect the rate of agonist-induced PAR1 ... Article and publication date are atwww.molbiolcell.org/cgi/doi/10.1091/mbc.
Published Online:18 Mar 2009https://doi.org/10.1091/mbc.e08-09-0969 ... The next day, cultures were treated or not with HGF/SF for 24 h. ... was published online ahead of print in MBC in Press (http://www.molbiolcell.org/cgi/doi/10.1091/mbc.
We also provide evidence that SLAP functions in a pathway that requires the phosphorylated TCRζ chain and the Src family kinase Lck, but not ZAP-70 (ζ- ...
While the mechanism by which CTLA-4 limits responses is not fully ... of CTLA4 Treg with APC caused the down-regulation of CD80/86 expression on the APC.
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Natural killer cells, also known as NK cells or large granular lymphocytes (LGL), are a type of ... In contrast to NKT cells, NK cells do not express T-cell antigen receptors (TCR) or ... A common evolutionary adaptation to this is seen in both intracellular microbes and tumors: the chronic down-regulation of MHC I molecules, ...
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26 May 2006 ... Importantly, the various proapoptotic effects of AIF were not inhibited by ... AIF knock-down partially protects cells from p53-mediated apoptosis. ... After 30 cycles of amplification, PCR products were run on a 2% agarose gel ...
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However, NK cells do not express the TCR, nor do they require MHC class I molecules on targets in order to kill them. In fact, MHC class I molecules on target cells ...
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... subclones 786‐O cells in which CCL2 expression was knocked down. Although CCL2 expression did not affect cell proliferation in vitro, CCL2 overexpression ...
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25 Mar 2019 ... ... stability of p21/cip1 in breast cancer cells via down-regulation of Akt ... berberine not only up-regulates mRNA and protein levels of p21/cip1 ...
