7 May 2019 ... Take down policy ... suggest lowering Lp(a) or inactivating OxPL may slow AS progression and provide a rationale for clinical trials to test this hypothesis. ... 73, NO. 17, 2019. Lp(a)/OxPL Aggravate Calcification in AS Patients.
29 Apr 2019 ... However, it remains unclear whether elevated Lp(a) and OxPL drive disease ... However, this finding has not been validated in the elderly patients ... lowering Lp(a) or OxPL in patients with elevated levels truly slows down AS ...
6 Jun 2018 ... Oxidized phospholipids (OxPL) are ubiquitous, formed in many inflammatory ... Plasma titers of the endogenous IgM E06 were not affected by the ... The cells were spun down on glass slides using cytospin (Thermo Shandon).
25 May 2017 ... This article briefly reviews the atherogenic mechanism of ox-LDL, the ... acid fragments, oxidized phospholipids (ox-PL), and oxygen free radicals. ... are not down regulated by elevated levels of intracellular cholesterol (Fig.
1 Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu, Shiga 520-2192, Japan. [email protected] ... All subjects completed the study with no adverse side effects. ... Biomarkers / metabolism; Cholesterol, LDL / blood; Down-Regulation / drug ...
However, measurements of Lp(a) are not widely available and are seldom used ... These trials did not show any clinical benefits of adding niacin to statin therapy. ... LDL level reduction still correlate with the CVD(because LDL level gets down ...
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26 Jun 2017 ... Oxidized phospholipids (OxPL) and lysophosphatidic... ... Autotaxin (ATX), which breaks down lysophosphatidylcholine (LysoPC) derived from OxPL to ... There are no effective medical therapies to prevent the development or ...
19 Dec 2016 ... The catabolic pathways for truncated ox-PLs are not fully understood. ... were added to a glass tube and dried down under a stream of nitrogen gas. ... PL liposomes containing 92 μM DODPC and 38 μM truncated ox-PL in the ...
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20 Apr 2017 ... Since these LDL-C cut-off points were not derived from Friedewald ... We suggest that an update to the current de facto LDL-C assessment will ...
14 Jul 2017 ... Here, OxPL were characterized as novel targets in acute and chronic inflammatory pain ... However, as the OxPAPC compounds PGPC and POVPC are not ... In mice, mechanical allodynia was measured by the up- and down ...
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16 Apr 2019 ... Especially since MepS was not part of the proteins being pulled down, and is known to bind to NlpI, we decided to investigate this further.
3 Feb 2020 ... All other proteins were coloured grey and not labelled to increase the plot ... NlpI pulls down several classes of PG hydrolases and multiple ...
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