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13 Apr 2018 ... Drugs that target ion channels involved in controlling heartbeats could help ... SK channels have no charged amino acids in the fourth TM domain, which is ... Down-regulation of the small conductance calcium-activated ...
We also provide evidence that SLAP functions in a pathway that requires the phosphorylated TCRζ chain and the Src family kinase Lck, but not ZAP-70 (ζ- ...
Medical University School of Medicine, 1-1. Yazakokarimata ... E-mail: [email protected]. (Received 14 ... tion assays suggest that C4BP interacts with TLR4/MD-2 but not TLR3. ... TLR ligand is bound, thereby activating TLR down-.
GST fusion protein preparation and Rap1 activation pull-down assay. ... We used a selective agonist, 8-pCPT, which activates EPAC but not PKA both in vitro ...
8 Apr 2013 ... Results HCV core protein up- or down-regulated some cellular microRNAs in ... Although p21Waf1/Cip1 deficiency may not be sufficient to ...
ER protein misfolding activates the Unfolded Protein Response (UPR) to help cells cope with ER stress. If ER homeostasis is not restored, UPR promotes cell ...
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With this model we are able to focus not only on the residues within the TM ... not exceed a value of 0.3 nm (Figure 1B). This is in ... down the pore from the N- to the C-terminus. ... Maldarelli, F., Chen, M. Y., Willey, R. L., and Strebel, K. (1993).
26 Nov 2019 ... Conflict-of-interest statement: The authors declare that they have no conflicts ... Integrata Verona, Verona 37126, Italy. [email protected] ... was 87.4 µA/cm², with a cut-off of 34 µA/cm² between non-CF and CF with ...
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Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions ...
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RTL9 (KIAA1318, Mar9, Mart9, RGAG1, SIRH10) protein expression summary. ... from Ensembl if not indicated otherwise. Gene name, RTL9 (HGNC Symbol).
... from Ensembl if not indicated otherwise. Gene name, MED24 (HGNC Symbol) ... at protein level). neXtProt, NX_O75448. Antibodypedia, MED24 antibodies ...
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