Ephrin-A1 Induces c-Cbl Phosphorylation and EphA Receptor Down ...

Ephrin-A1 Induces c-Cbl Phosphorylation and EphA Receptor Down ...

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Ephrin-A1 Induces c-Cbl Phosphorylation and EphA Receptor Down ...

15 Jun 2003 ... ... (12) 6024-6032; DOI: https://doi.org/10.4049/jimmunol.170.12.6024 ... Receptor down-regulation could also be inhibited by blockage of Src family kinase activity. ... Induction of Cbl phosphorylation upon ephrin-A stimulation, but not ... Miao, H., B. R. Wei, D. M. Peehl, Q. Li, T. Alexandrou, J. R. Schelling, ...

Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ...

proLékaře.cz proLékaře.cz ... The cellular clearance pathways, e.g. autophagy-lysosomal pathway, may not be of high efficiency in the ... In the absence of ULK1, anti-ULK1 antibody did not pull down p62 in ULK1 knock-out(KO) MEFs [38], ...

Identification of Liver X Receptor-Retinoid X Receptor as an ... - UMIN

Tennodai, Tsukuba, Ibaraki 305-8575, Japan. Phone and fax: 81-298- ... In contrast, down-regulation of SREBP-1c was observed in livers from fasted rodents, ... SREBP-1c promoter, indicating that this sequence was not in- volved. In contrast ...

Differential Phosphorylation Provides a Switch to Control How α ...

24 Feb 2016 ... ... haploids to the peptide mating pheromone α-factor, is down-regulated by both ... Hence, it was not at all clear whether Snf1 phosphorylation of Rod1 has any ... (CN)-deficient cells (see later section Calcineurin dephosphorylates the ... response to heat stress via the Pkh-Ypk and Cdc55–PP2A pathways.

Phosphorylation of β-Tubulin by the Down Syndrome Kinase ...

21 Apr 2016 ... Phosphorylation of β-Tubulin by the Down Syndrome Kinase, ... Interestingly, MNB is expressed in the class III, but not the class IV da ... B (0.08% formic acid in 80% acetonitrile) at a flow rate of 300 nL/min. ... Witucki L, Kung C, Shokat KM. Design of allele-specific inhibitors to probe protein kinase signaling.

ATM-mediated KDM2A phosphorylation is required for the DNA ...

30 Mar 2015 ... E-mail: [email protected]. 5These authors ... down did not affect H3K36me2 levels after etoposide treatment. (Supplementary Figure ...

Plk1-mediated Phosphorylation ofToporsRegulatesp53Stability*DS

down by the anti-GFP antibody from lysates of cells expressing. GFP-Topors, indicating ... DS The on-line version of this article (available at http://www.jbc.org) contains ... fragment of Topors is not phosphorylated in vivo (supple- · mental Fig.

Protein Phosphorylation in Serine Residues Correlates with ...

12 Mar 2020 ... 2Universidad Autónoma de la Ciudad de México (UACM), Plantel Cuautepec, Ciudad de México 07160, ... proteins identified in LSIL, HSIL, and CC but that are not ... down using the antisense oligonucleotide OGX-011 re-.

Diacylglycerol kinase- α phosphorylation by Src on Y335 is required ...

13 Aug 2007 ... Upon coexpression with Src, Myc-Dgk-α-Y335F does not feature any ... Myc-Dgk-α wt was pulled down by GST-SrcSH2, but not by GST alone, ... Ohashi M, Jan de Vries K, Frank R, Snoek G, Bankaitis V, Wirtz K et al. (1995).

Structural Basis for Control by Phosphorylation - Unisciel

karyotes, the protein kinase domain responsible for ... kinases that are not regulated by phosphorylation ... activity and this activity was not down regulated by.

MED1 Phosphorylation Promotes Its Association with Mediator ...

GST pull-down assays with 35S-labeled or baculovirus-expressed proteins ... MED1 phosphorylation is required for NR coactivator activity, but not for NR binding. ... Migliaccio, A., G. Castoria, M. Di Domenico, A. De Falco, A. Bilancio, and F.

Reproductive status impact on tau phosphorylation induced by ...

20 Jul 2020 ... To test the hypothesis that reproductive status can impact hippocampal ... Because no differences were detected in response to stress by lactating rats ... Y. Yan, S. Dominguez, D.W. Fisher, H. DongSex differences in chronic ...

Phosphorylation of OPTN by TBK1 enhances its binding to Ub ...

30 Mar 2016 ... WT OPTN, but not an ALS-associated, Ub-binding deficient mutant ... (D) GST–OPTN 1–170 pull-down as in A, including TBK1 mutant delta690-713. ... Cell Function and Dynamics, Brain Science Institute (BSI), RIKEN, Japan], ...

Frequency-Dependent ERK Phosphorylation in ... - Molecular Pain

(page number not for citation purposes). Molecular ... Yi Dai - [email protected]; Koichi Iwata - [email protected]; ... down is typically observed [19].

MERTK mediated novel site Akt phosphorylation alleviates SAV1 ...

3 Apr 2019 ... Binding to a proline-tyrosine motif in the Akt-PH domain, SAV1 ... Our observed SAV1-mediated suppression of Akt activation may not function ...

OST1‐mediated BTF3L phosphorylation positively regulates CBFs ...

5 Mar 2018 ... OST1 protein was pulled down by GST‐BTF3L but not GST (Fig 1B). Additional evidence that BTF3L interacts with OST1 came from split ...

LATS kinase–mediated CTCF phosphorylation and selective loss of ...

19 Feb 2020 ... 1G), implying that phosphorylation may not affect CTCF protein ... we used a stringent threshold for peak calling and identified 11,880 ... (C) Depletion of YAP in MCF7 cells down-regulates its target genes. ... Knockdown efficiency and YAP target gene expression were determined by quantitative RT-PCR.

Tumor necrosis factor-α induces MMP-9 expression via p42/p44 ...

9 Feb 2008 ... Fax: 3 2118365. E-mail address: [email protected] (C.-M. Yang). ... MMP-2 is constitutively expressed by several cell types and not inducible ... MEK1 and p42 down-regulated the expression of MEK1 and p42 and ...

Intermittent Hypoxia Induces Proteasome-Dependent Down ...

down-regulation of ER- that is not attributable to de- creased ... However, ER-–negative status in in situ cancer is associated ... clincancerres.aacrjournals.org.

5/6 nephrectomy induces different renal, cardiac and vascular ...

30 Jan 2020 ... Heart weight increased significantly only in 129/Sv mice. ... Increase in albuminuria was significant in 129/Sv but not in C57BL/6JRj mice. Both strains ... Off. Publ. Eur. Dial. Transpl. Assoc. - Eur. Ren. Assoc. 26, 3537–3543 (2011). ... Timmermans, S., Van Montagu, M. & Libert, C. Complete overview of ...

Prostasin induces protease-dependent and ... - ScienceDirect.com

https://doi.org/10.1016/j.bbamcr.2007.04.013Get rights and content ... The human prostate carcinoma cell line PC-3 (Passage 18) was obtained from the ... For COX-2 the down-regulation by the mutant prostasin was not as great as that by the ...

Cytotoxicity of naringenin induces Bax‐mediated mitochondrial ...

15 Jul 2020 ... ... of NGEN in cell death of lung cancer cells have not been fully defined. ... intensely upregulated Bax and down‐regulated Bcl‐2 proteins were ...

5/6 nephrectomy induces different renal, cardiac and ... - Nature

Increase in albuminuria was significant in 129/Sv but not in C57BL/6JRj mice. ... but these models do not fully reproduce the CV consequences of CKD observed in humans, ... Transplant. Off. Publ. Eur. Dial. Transpl. Assoc. - Eur. Ren. Assoc., https://doi. ... Timmermans, S., Van Montagu, M. & Libert, C. Complete overview of ...

Hsp90 induces increased genomic instability toward DNA-damaging ...

Published Online:15 Jun 2016https://doi.org/10.1091/mbc. ... However, how hyperthermia induces DNA damage sensitivity is not clear. ... Hsp90 causes down-regulation of Rad53 in a dose-dependent manner ... article was published online ahead of print in MBoC in Press (http://www.molbiolcell.org/cgi/doi/10.1091/mbc.

Spaceflight Induces Specific Alterations in the Proteomes of ... - NCBI

While there is not a one-to-one correlation with any gene set from a published ... S1; supplementary data are available online at www.liebertonline.com/ast). ... In those same root samples, 121 proteins were found to be down-regulated and ...

Lysyl oxidase induces epithelial‐mesenchymal transition and ...

28 Mar 2019 ... Staining intensity was scored according to the following criteria: 0 (no staining, negative); 1 ... Sk‐hep1 cells of density of 4.0 × 104 cells/mL were cultured in Eagle's ... Technologies, Kumamoto, Japan) according to the manufacturer's protocols. ... Conversely, knocking down of LOX did not suppress HIF‐1α ...

A diet change from dry food to beef induces ... - Voerwijzer.com

23 May 2017 ... Three dogs did not contribute with samples from all diet periods due to a faecal score > 4.5 two consecutive times. One dog (no. 8) was taken off ...

Acyclic retinoid induces differentiation and apoptosis of murine ...

26 Mar 2015 ... 11 Advanced Medical Research Center, Yokohama City University, Yokohama, Kanagawa, 236-0004, Japan. [email protected].

Ocean acidification at a coastal CO2 vent induces expression of ...

8 May 2019 ... (A) The sea anemone Anemonia viridis growing at high CO2 (mean pH 7.6) at 1 m depth. ... We infer that the host-symbiont relationship is not disrupted at low ... Down-regulation of transcripts from seawater pH 8.2 to either pH 7.6 or pH ... Moya A, Huisman L, Foret S, Gattuso JP, Hayward DC, Ball EE, et al.

Combination of Tumor Necrosis Factor α and Interleukin‐6 Induces ...

7 Oct 2013 ... Small interfering RNA was used to knock down c‐Fos. ... available at http://www.saitama‐med.ac.jp/uinfo/riumachi/supplementary_figure.html). ... Dependence of osteoclast‐like cells, but not conventional osteoclasts, on JAK.

HCV non-structural NS4A protein of genotype 3a induces ... - PubMed

1 Sep 2018 ... Electronic address: [email protected]. ... NS3-4A and NS4A proteins were not only localized on ER but also on the mitochondria. ... expression of Bax and down-regulated expression of anti-apoptotic Bcl-xL protein ...

Agrin induces association of Chrna1 mRNA and nicotinic ...

21 Sep 2012 ... Briefly, agrin-induced fold enrichment of Chrna1 mRNA in pull down ... In agreement with previous studies [23], [24], agrin did not alter the levels of ... J.P. Merlie, J.R. SanesConcentration of acetylcholine receptor mRNA in ...

CGRP Induces Differential Regulation of Cytokines From Satellite ...

7 Feb 2019 ... ... Tokushima 770-8504, Japan. [email protected]. ... thermal nociception, glial activity, and down-regulated IL-1β and IL-6 cytokines ...

TAVI induces an elevation of hemostasis-related biomarkers, which ...

5 Jul 2016 ... The frequent finding of post-TAVI thrombocytopenia appears not to be ... and platelet activation after on-pump and off-pump coronary artery ...

Bryonia dioica aqueous extract induces apoptosis through ...

(cleaved forms expressed) but not caspase 8. ... The authors declare that there are no conflicts of interest. ... Down-regulation of Bim expression relationship.

Ouabain Induces Apoptotic Cell Death Through Caspase- and ...

Science and Technology, China Medical University, No 91, Hsueh-Shih. Road, Taichung ... 5850, Fax: 886 228264517, e-mail: [email protected]. Key Words: Ouabain ... death, via Mcl-1 down-regulation (8). Moreover, inhibition of.

Ginsenoside Rh2 induces Bcl-2 family proteins-mediated apoptosis ...

... however, their molecular mechanisms in vitro and in in vivo models are not well studied. ... Chungnam National University, Daejeon 301747, Korea. [email protected] ... Rh2-induced apoptosis was accompanied by the down-regulation of ...

Combined arginine and ascorbic acid treatment induces apoptosis ...

ultimate effect of NO on tumor cell survival is dictated by multiple factors, including levels of NO ... [email protected], [email protected]. (K.-L. Chang). ... incubated with drugs for 6 h, scraped off and centrifuged. The cell pellet was ...

Stocking density induces differential expression of immune-related ...

Electronic address: [email protected]. ... immunocompetence of the skeletal muscle has not been studied in detail in earlier vertebrates. ... The results indicate that chronic stress down-regulates the expression of these genes in muscle, ...

Induces Apoptotic Cell Death of Human Hepatoma p53 Mutant ...

Kaohsiung County 831, Taiwan, Graduate Institute of Medical Biotechnology, Chang ... [email protected] (S.-H.K.). ... whether or not 6-SG can exert a carcinogenic effect. ... reactive oxygen species and down-regulation of NF-κB signaling.

Retinoic Acid Induces Embryonic Stem Cell Differentiation by ...

10 Jul 2015 ... Although RA does not regulate many histone modifiers at the mRNA level, ... down induced neuroectodermal markers for gene upregulation [45, 46]. ... Team in Shaanxi Province (2014KCT-26) (http://www.sninfo.gov.cn/).

Calreticulin and integrin alpha dissociation induces anti ... - Nature

17 May 2018 ... Previous studies suggested that CRT is not only localized in the endoplasmic ... was purchased from RIKEN Cell Bank and Dainippon Pharmaceutical Co., Ltd. Cells were tested ... GST pull-down assay and western blotting ... Jun-Dal Kim, Yuki Hayashi, Hayase Mizukami, Keiji Kimura & Akiyoshi Fukamizu.

Caffeine exposure induces browning features in adipose tissue in ...

24 Jun 2019 ... In vivo, drinking coffee (but not water) stimulated the temperature of the supraclavicular region, which co-locates to the main region of BAT in ...

Penta-galloyl-glucose induces autophagy and caspase ... - NCBI

Hongbo Hu, Yubo Chai, [. ... Penta-O-galloyl-β-D-glucose (PGG) suppresses the in vivo growth of human DU145 and PC-3 prostate cancer ... However, knocking down RIP1 did not alter LC3-II level, nor did it increase PARP cleavage (Fig. 4E).

Motor skill learning induces brain network plasticity: A ... - PLoS

6 Feb 2019 ... 4 [email protected] (JZ); [email protected] (HZ). Abstract. Motor skills and the ... National Natural Science Foundation of China (no. 31371056, no. 31470051, no. ... Top-down modulation of early sensory cortex.

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